Course Material
Now online: Pre-Course Homework and MATLAB exercises
A schedule for the work, which should be done before the course, including reading material, information on how to learn Matlab, and Matlab exercises can be found here http://www.debtox.info/board/viewtopic.php?f=19&t=41
Note that the time needed for the Matlab exercises is part of the preparation time noted in the work load of the course!
Discussion forum
Please register for the DEBtox discussion board, which contains a dedicated sub-forum for the course. This board offers a platform for discussions and asking questions. Furthermore, announcements concerning the course as well as information on the homework are published on this board (see above). Use the dedicated topic in the announcements to introduce yourself to us and the other participants.
Modelling program
Within the course we will use the program MATLAB. As soon as the participant has payed the course fees he/ she will receive an ID, which is required for the download of MATLAB. All students have to bring their own laptop. Please install the program on your laptop and go through the MATLAB tutorials and exercises before the course starts
If you are new to MATLAB, make sure you start with the first four chapters of the MATLAB tutorial. Make sure you learn how the MATLAB environment works, how to write a script, how to work with matrices, how to make simple plots, and how to work with operators such as "if" statements and "for" loops. This means at minimum most of the Chapters 1 and 2, only the most basic plotting functions of Chapter 3, only "flow control" and the basics of "scripts and functions" of Chapter 4. Note that the time needed for this is on top of the preparation time noted in the work load of the course!
After the course, if you do not have access to MATLAB, you can download the freeware Octave, which has roughly the same capabilities (but lacks the effective editor, help function and debugger of MATLAB).
Literature
The following papers give a good introduction to the topic and should be read before the course:
- Jager T, Heugens EHW, Kooijman SALM. 2006. Making sense of ecotoxicological test results: Towards application of process-based models. Ecotoxicology 15: 305-314. (PDF)
- Ashauer R, Escher BI. 2010. Advantages of toxicokinetic and toxicodynamic modelling in aquatic ecotoxicology and risk assessment. Journal of Environmental Monitoring 12:2056-2061. (PDF)
Refresher on differential equations and likelihood functions can be found here: refresher.pdf
Further literature about toxicokinetic/ toxicodynamic modelling and DEBtox, can be found here www.debtox.info
Andreas C. Kretschmann, - last update:16 May 2012